A murderer of women is going around in Venice. The investigations are taken up by Inspector Datti. The girlfriend of the successful pianist Robert Dominici is also found dead. As more murders occur, Robert learns he has an incurable disease. In a very short time his mind and his body fall into the state of an old man. Robert's psyche begins to change. How are the murders related to Robert's illness. Inspector Datti is literally driven insane by the killer and has his hands full!